Publication

  1. H. Tsuchiya, N. Nakamura, S. Ohta*

    "Centrifugal Field-Flow Fractionation Enables Detection of Slight Aggregation of Nanoparticles That Impacts Their Biomedical Applications"

    Anal. Chem., (in press)

  2. N. Nakamura, S. Ohta

    "Precise control methods of the physicochemical properties of nanoparticles for personalized medicine"

    Current Opinion in Biotechnology, 87 (2024) 103108.

  3. Y. Maeda, N. Nakamura, S. Ohta*

    "DNA-Mediated, on-Membrane Sequential Assembly of Conjugated Polymer Nanoparticles for Sensitive Detection of Cell Surface Markers"

    Adv. Funct. Mater., (2024) 2315160.

  4. K. Fujiura, M. Naito, Y. Tanaka, M. Tanaka, Y. Nakanishi, H. Ejima, L. Negishi, T. Kujirai, H. Kurumizaka, S. Ohta, K. Miyata

    "Development of stealth nanoparticles coated with poly(2-methoxyethyl vinyl ether) as an alternative to poly(ethylene glycol)"

    J. Appl. Polym. Sci., (2023) e55044.

  5. A. K. S. Chandel, A. S. Madhavikutty, S. Okada, Z. Qiming, N. F. Inagaki, S. Ohta, T. Ito

    "Injectable, shear-thinning, photocrosslinkable, and tissue-adhesive hydrogels composed of diazirine-modified hyaluronan and dendritic polyethyleneimine"

    Biomater. Sci., 12 (2024) 1454-1464.

  6. K. Okamura, H. Tsuchiya, R. Hamada, Y. Hayashi, S. Badr, S. Ohta, H. Sugiyama

    "A systems evaluation model for the development of companion diagnostics and associated molecularly targeted therapies"

    J. Pharm. Innov., 199 (2023) 507.

  7. Q. Pan, Y. Tsuji, A. S. Madhavikutty, S. Ohta, A. Fujisawa, N. F. Inagaki, M. Fujishiro, T. Ito

    "Prevention of esophageal stenosis via in situ cross-linkable alginate/gelatin powder in a new submucosal exfoliation model in rats"

    Biomater. Sci., 11 (2023) 6781.

  8. N. Nakamura, R. Hamada, H. Kaneko, S. Ohta*

    "Selecting optimum miRNA panel for miRNA signature-based companion diagnostic model to predict the response of R-CHOP treatment in diffuse large B-cell lymphoma"

    J. Biosci. Bioeng., 4 (2023) 341.

  9. A. S. Madhavikutty, A. K. S. Chandel, C.-C. Tsai, N. F. Inagaki, S. Ohta, T. Ito

    "pH responsive cationic guar gum-borate self-healing hydrogels for muco-adhesion"

    Sci. Tech. Adv. Mater., 24 (2023) 2175586.

  10. H. Fujita, S. Ohta, N. Nakamura, M. Somiya, M. Horie

    "Progress of endogenous and exogenous nanoparticles for cancer therapy and diagnostics"

    Genes., 14 (2023) 259.

  11. N. Nakamura, S. Ohta, M. Yamada, Y. Suzuki, N. F. Inagaki, T. Yamaguchi, T. Ito

    "Development of a potassium ion-responsive star copolymer with controlled aggregation/dispersion transition"

    ACS Omega., 8 (2023) 1343.

  12. M. Okawa, A. Tanabe, S. Ohta, S. Nagatoishi, K. Tsumoto, T. Ito

    "Extracellular matrix-inspired hydrogel of hyaluronan and gelatin crosslinked via a Link module with a transglutaminase reactive sequence"

    Communications Materials., 3 (2022) 81.

  13. A. K. S. Chandel, S. Ohta, M. Taniguchi, H. Yoshida, D. Tanaka, K. Omichi, A. Shimizu, M. Isaji, K. Hasegawa, T. Ito

    "Balance of antiperitoneal adhesion, hemostasis, and operability of compressed bilayer ultrapure alginate sponges"

    Biomaterials Adv., 137 (2022) 212825.

  14. N. Nakamura, N. Tanaka, S. Ohta*

    "Facile and wide-range size tuning of conjugated polymer nanoparticles for biomedical applications as a fluorescent probe"

    RSC Adv., 12 (2022) 11606.

  15. M. Horie, N. Yamano-Adachi, Y. Kawabe, H. Kaneoka, H. Fujita, E. Nagamori, R. Iwai, Y. Sato, K. Kanie, S. Ohta, M. Somiya, K. Ino

    "Recent advances in animal cell technologies for industrial and medical applications"

    J. Biosci. Bioeng.,6 (2022) 509.

  16. S. Ohta, K. Mitsuhashi, A. S. Chandel, P. Qi, N. Nakamura, A. Nakamichi, H. Yoshida, G. Yamaguchi, Y. Hara, R. Sasaki, M. Fuke, M. Takai, T. Ito

    "Silver-Loaded Carboxymethyl Cellulose Nonwoven Sheet with Controlled Counterions for Infected Wound Healing"

    Carbohydrate Polymers,286 (2022) 119289.

  17. Y. Amano, K. Sakura, S. Ohta, T. Ito

    "Cisplatin-chelated iminodiacetic acid-conjugated hyaluronic acid nanogels for the treatment of malignant pleural mesothelioma in mice"

    Molecular Pharmaceutics,19 (2022) 853.

  18. Y. Nakagawa, Y. Oki, X. Da, A. K. S. Chandel, S. Ohta, T. Ito

    "Injectable bottlebrush triblock copolymer hydrogel crosslinked with ferric ions"

    Polymer, 240 (2022) 124519.

  19. K. Mitsuhashi, S. Ohta, T. Ito

    “Analysis of permeation of model drugs through highly crosslinked and biodegradable polyethylene glycol membranes”

    J. Membr. Sci., 645 (2022) 120218.

  20. X. Fu, S. Ohta, T. Kawakatsu, M. Kamihira, Y. Sakai, T. Ito

    “Bioinspired perfluorocarbon-based oxygen carriers with concave shape and deformable shell”
    Adv. Mater. Technol., 7 (2021) 2100573.

  21. K. Yamaguchi, O. Hiraike, H. Iwaki, K. Matsumiya, N. Nakamura, K. Sone, S. Ohta, T. Ito, Y. Osuga

    "Intraperitoneal administration of cisplatin-loaded nanogel through a hybrid system containing alginic acid-based nanogel and in situ cross-linkable hydrogel for peritoneal dissemination of ovarian cancer"
    J. Mol. Pharmaceut., 18 (2021) 4090.

  22. A. M. Sreedevi, S. Ohta, A. K. S. Chandel, P. Qi, and T. Ito

    "Analysis of endoscopic injectability and post-ejection dripping of yield stress fluids: laponite, carbopol and xanthan gum"
    J. Chem. Eng. Jpn., 54 (2021) 500.

  23. T. Hozumi, A. M. Sreedevi, S. Ohta, and T. Ito

    "Nonlinear Pressure-drop Oscillations during Gelation in a Kenics Static Mixer"
    Indust. Eng. Chem. Res., 59 (2020) 10.

  24. S. Ohta, E. Kikuchi, A. Ishijima, T. Azuma, I. Sakuma, and T. Ito

    "Investigating the optimum size of nanoparticles for their delivery into the brain assisted by focused ultrasound-induced blood?brain barrier opening"
    Sci. Rep., 10 (2020) 18220.

  25. M. Okawa, M. Sakoda, S. Ohta, K. Hasegawa, Y. Yatomi, and T. Ito

    "The balance between the hemostatic effect and immune response of hyaluronan conjugated with different chain lengths of inorganic polyphosphate"
    Biomacromol., 21 (2020) 2694.

  26. K. Mitsuhashi, P. Qi, A. Takahashi, S. Ohta, and T. Ito

    "Prevention of postoperative peritoneal adhesions in rats with sidewall defect-bowel abrasions using metal ion-crosslinked N-succinyl chitosan hydrogels"
    React. Funct. Polym. 145 (2019) 104374.

  27. P. Qi, Y. G. Zheng, S. Ohta, N. Kokudo, K. Hasegawa, and T. Ito

    "The In situ fabrication of double-layered hydrogels via spray processes to prevent postoperative peritoneal adhesion"
    ACS Biomater. Sci. Eng. 5 (2019) 4790.

  28. Y. Amano, S. Ohta, K. L. Sakura, and T. Ito

    "The Pemetrexed-conjugated hyaluronan for the treatment of malignant pleural mesothelioma"
    Eur. J. Pharm. Sci. 138 (2019) 105008.

  29. Y. Oki, K. Kirita, S. Ohta, S. Ohba, I. Horiguchi, Y. Sakai, and T. Ito

    "Switching of cell proliferation/differentiation in thiol-maleimide clickable microcapsules triggered by in situ conjugation of biomimetic peptides"
    Biomacromol. 20 (2019) 2350?2359.

  30. S. Ohta, T. Toda, F. Inagaki, K. Omichi, A. Shimizu, N. Kokudo, K. Hasegawa, and T. Ito

    "The Prevention of Hepatectomy-induced Adhesions by Bilayer Sponge Composed of Ultrapure Alginate"
    J. Surg. Res. 242 (2019) 286?295.

  31. S. Ohta, M. Matsuura, Y. Kawashima, M. Taniguchi, H. Okochi, Y. Asano, S. Sato, and T. Ito

    "Facile fabrication of PEG-coated PLGA microspheres via SPG membrane emulsification for the treatment of scleroderma by ECM degrading enzymes"
    Coll. Surf. B Biointerfaces 179 (2019) 453?461.

  32. D. Glancy, Y. Zhang, J. L. Y. Wu, B. Ouyang, S. Ohta, and W. C. W. Chan

    "Characterizing the protein corona of sub-10 nm nanoparticles"
    J. Control. Release 304 (2019) 102?110.

  33. F. Tanaka, Y. Nakagawa, S. Ohta, and T. Ito

    "Thermoreversible gelation with ion-binding cross-links of variable multiplicity"
    J. Chem. Phys. 150 (2019) 174904.

  34. X. Fu, S. Ohta, M. Kamihira, Y. Sakai,and T. Ito

    "Size-controlled Preparation of Micro-sized Perfluorocarbon Emulsions as Oxygen Carriers via SPG Membrane Emulsification Technique"
    Langmuir 35 (2019) 4094?4100.

  35. A. Sakamoto, P. Qi, S. Ohba, S. Ohta, Y. Hara, T. Ogawa, M. Tomokiyo, A. Sasaki, H. Takizawa, M. Mochizuki, T. Ito and M. Honnami

    "Bone Regeneration by Calcium Phosphate-Loaded Carboxymethyl Cellulose Nonwoven Sheets in Canine Femoral Condyle Defects"
    J. Biomed. Mater. Res. Part B 107 (2019) 1516?1521.

  36. Y. Amano, P. Qi, Y. Nakagawa, K. Kirita, S. Ohta, and T. Ito

    "Prevention of Peritoneal Adhesions by Ferric Ion-crosslinked Hydrogels of Hyaluronic Acid Modified with Iminodiacetic Acids"
    ACS Biomater. Sci. Eng. 4 (2018) 3405?3412.

  37. M. Sakoda, M. Kaneko, S. Ohta, P. Qi, S. Ichimura, Y. Yatomi, and T. Ito

    "An Injectable Hemostat Composed of a Polyphosphate-Conjugated Hyaluronan Hydrogel"
    Biomacromol. 19 (2018) 3280-3290.

  38. S. Ohta, K. Hashimoto, X. Fu, M. Kamihira, Y. Sakai, and T. Ito

    "Development of Human-derived Hemoglobin-Albumin Microspheres as Oxygen Carriers Using Shirasu Porous Glass Membrane Emulsification"
    J. Biosci. Bioeng. 126 (2018) 533?539.

  39. P. Qi, S. Ohba, Y. Hara, M. Fuke, T. Ogawa, S. Ohta, and T. Ito

    "Fabrication of calcium phosphate-loaded carboxymethyl cellulose non-woven sheets for bone regeneration"
    Carbohydr. Polym. 189 (2018) 322-330.

  40. Y. Amano, Y. Nakagawa, S. Ohta, and T. Ito

    "Ion-responsive fluorescence resonance energy transfer between grafted polyacrylic acid arms of star block copolymers"
    Polymer 137 (2018) 169-172.

  41. T. Hozumi, T. Kageyama, S. Ohta, J. Fukuda, and T. Ito

    "An Injectable Hydrogel with Slow Degradability Composed of Gelatin and Hyaluronic Acid Crosslinked by Schiff’s Base Formation"
    Biomacromol. 19 (2018) 288-297.

  42. Y. Nakagawa, S. Ohta, M. Nakamura, and T. Ito

    " 3D inkjet printing of star block copolymer hydrogels cross-linked using various metallic ions"
    RSC Adv. 7 (2017) 55571-55576.

  43. S. Ohta, S. Hiramoto, Y. Amano, S. Emoto, H. Yamaguchi, H. Ishigami, J. Kitayama, and T. Ito

    "Intraperitoneal delivery of cisplatin via a hyaluronan-based nanogel/in situ crosslinkable hydrogel hybrid system for peritoneal dissemination of gastric cancer"
    Mol. Pharm. 14 (2017) 3105-3113.

  44. Y. Nakagawa, S. Ohta, A. Sugahara, M. Okubo, A. Yamada, and T. Ito

    "In vivo redox-responsive sol-gel/gel-sol transition of star block copolymer solution based on ionic cross-linking"
    Macromol. 50 (2017) 5539-5548.

  45. S. Wilhelm, A. J. Tavares, Q. Dai, S. Ohta, J. Audet, H. F. Dvorak, and W. C. W. Chan

    "Analysis of nanoparticle delivery to tumours"
    Nature Reviews Materials 1 (2016) 16014.

  46. S. Ohta, D. Glancy, and W. C. W. Chan

    "DNA-controlled dynamic colloidal nanoparticle systems for mediating cellular interaction"
    Science 351 (2016) 841-845.

  47. S. Ohta, S. Hiramoto, Y. Amano, M. Sato, Y. Suzuki, M. Shinohara, S. Emoto, H. Yamaguchi, H. Ishigami, Y. Sakai, J. Kitayama, and T. Ito

    "Production of cisplatin-incorporating hyaluronan nanogels via chelating ligand-metal coordination"
    Bioconjug. Chem. 27 (2016) 504-508.

  48. Y.-T. Lai, S. Ohta, K. Akamatsu, S. Nakao, Y. Sakai, and T. Ito

    "Size-dependent interaction of cells and hemoglobin-albumin based oxygen carriers prepared using the SPG membrane emulsification technique"
    Biotechnol. Prog. 31 (2015) 1676-1684.

  49. Y. Nakagawa, Y. Amano, S. Nakasako, S. Ohta, and T. Ito

    "Biocompatible star block copolymer hydrogel cross-linked with calcium ions"
    ACS Biomater. Sci. Eng. 1 (2015) 914-918.

  50. S. Ohta, K. Yamura, S. Inasawa and Y. Yamaguchi

    "Aggregates of silicon quantum dots as a drug carrier: selective intracellular drug release based on pH-responsive aggregation/dispersion"
    Chem. Commun. 51 (2015) 6422-6425.

  51. S. Ohta, S. Inasawa and Y. Yamaguchi

    "Alignment of vascular endothelial cells as a collective response to shear flow"
    J. Phys. D: Applied Physics 48 (2015) 245401.

  52. T. Hozumi, S. Ohta, and T. Ito

    "Analysis of the calcium alginate gelation process using a Kenics static mixer"
    Indust. Eng. Chem. Res. 54 (2015) 2099-2107.

  53. Y.-T. Lai, M. Sato, S. Ohta, K. Akamatsu, S. Nakao, Y. Sakai, and T. Ito

    "Preparation of uniform-sized hemoglobin?albumin microspheres as oxygen carriers by Shirasu porous glass membrane emulsification technique"
    Colloid. Surf. B 127 (2015) 1-7.

  54. A. T.H. Wu, T. Aoki, M. Sakota, S. Ohta, S. Ichimura, T. Ito, T. Ushida, and K. S. Furukawa

    "Enhancing osteogenic differentiation of MC3T3-E1 cells by immobilizing inorganic polyphosphate onto hyaluronic acid hydrogel"
    Biomacromol. 16 (2015) 166-173.

  55. S. Ohta, T. Nishiyama, M. Sakoda, K. Machioka, M. Fuke, S. Ichimura, F. Inagaki, A. Shimizu, K. Hasegawa, N. Kokudo, M. Kaneko, Y. Yatomi, amd Taichi Ito

    "Development of carboxymethyl cellulose non-woven sheets as a novel hemostatic sgent"
    J. Biosci. Bioeng. 119 (2015)

  56. Y. Nakagawa, S. Nakasako, S. Ohta, and T. Ito

    "A Biocompatible calcium salt of hyaluronic acid grafted with polyacrylic acid"
    Carbohydr. Polym. 117 (2015) 43-53.

  57. A. Takahashi, Y. Suzuki, T. Suhara, K. Omichi, A. Shimizu, K. Hasegawa, N. Kokudo, S. Ohta, and T. Ito

    "In situ cross-linkable hydrogel of hyaluronan produced via copper-free click chemistry"
    Biomacromol. 14 (2013) 3581-3588.

  58. Y.-T. Lai, S. Ohta, K. Akamatsu, S. Nakao, Y. Sakai, and T. Ito

    "Preparation of uniform-sized poly[methacryloxypropyl tris(trimethylsiloxy)silane] microspheres via Shirasu porous glass membrane emulsification technique"
    J. Chem. Eng. Jpn. 46 (2013) 777-784.

  59. S. Ohta, S. Inasawa, and Y. Yamaguchi

    "Real time observation and kinetic modeling of the cellular uptake and removal of silicon quantum dots"
    Biomaterials 33 (2012) 4639-4645.

  60. S. Ohta, P. Shen, S. Inasawa, and Y. Yamaguchi

    "Size- and surface chemistry-dependent intracellular localization of luminescent silicon quantum dot aggregates"
    J. Mater. Chem. 22 (2012) 10631-10638.

  61. S. Ohta, S. Inasawa, and Y. Yamaguchi

    "Size control of phase-separated liquid crystal droplets in a polymer matrix based on the　phase diagram"
    J. Polym. Sci. Part B: Polym. Phys. 50 (2012) 863-869.

  62. P. Shen, S. Ohta, S. Inasawa, and Y. Yamaguchi

    "Selective labeling of the endoplasmic reticulum in live cells with silicon quantum dots"
    Chem. Commun. 47 (2011) 8409-8411.

  63. S. Ohta, S. Inasawa, O. Koike, M. Fujita, and Y. Yamaguchi

    "Formation of well-aligned thin films of rod-like nanoparticles via solvent evaporation: A simulation study"
    Appl. Phys. Express. 2 (2009) 065002-1-3.

  64. O. Koike, S. Ohta, M. Fujita, and Y. Yamaguchi

    "Simulation Model of concentrated colloidal rod-Like nanoparticles"
    Jpn. J. Appl. Phys. 47 (2008) 8124-8130.